Useful Information

Immunotherapy against cancer: boosting the immune system

In fact, immotherapy against cancers act by different methods, such as that of stimulating immunity . We talk about active immunotherapy . It consists of directing and directing the action of the immune system to increase its effects against cancer. For this, doctors use substances, such as cytokines that "boost" immunity.

This type of treatment is the subject of numerous researches around the world and in France. Researchers are particularly interested in one type of white blood cell: T8 lymphocytes.

Raise the brakes preventing the immune system from acting

Another way used by immunotherapy is to remove the brakes that prevent the immune system from acting fully in certain cancers. In this area, we also see many new drugs arrive ... These block proteins present on white blood cells (lymphocytes) and will thus remove the brake that prevents the immune system from acting fully against cancer.

These drugs that block PD-1 or CTLA-4 proteins are called nivolumab or ipilmumab. Work has shown their activity in melanomas, certain lung cancers, ENT cancers, and are under study in many other tumors. It should be noted that the effectiveness of these treatments increases when they are combined.

Other avenues of research concern so-called therapeutic vaccination. It is an anti-cancer immunotherapy that acts specifically against cancer, with the aim of destroying diseased cells. This treatment is not yet available for patients, as research is still needed. These studies are done on lung cancer, melanoma, etc.

Immunotherapy against cancer is a growing discipline. It is now part of the therapeutic arsenal anti-cancer. And we still expect a lot of research on immunotherapy.

In oncology, many new drugs related to this immunotherapy are under development. Very often it is seen that the results are better when using several immunotherapy drugs to prevent the phenomena of resistance to treatment.

You want to react, to give your testimony or to ask a question? See you in our FORUMS Cancer or A doctor answers you !

Read also :

> True / False about chemotherapy
> Radiation therapy: limiting side effects

Sources and notes

> Sandler A, et al. Paclitaxel-carboplatin alone with bevacizumab for non-small-sell lung cancer. New England Journal of Medicine. 2006. Inca.
> Inca website 2015.
> J.Larkin et al, Combined Nivolumab and Ipilumumab or Monoptherapy in Untreated Melanoma, New England Journal of Medicine, May 31, 2015.

Popular Posts

Category Useful Information, Next Article

The spleen: An increase in volume - Useful Information
Useful Information

The spleen: An increase in volume

The spleen can increase in volume - it is called splenomegaly, in some diseases. As in the case of infectious mononucleosis. But also other infectious diseases, such as leishmaniasis, or in case of diseases with excessive destruction of red blood cells. Or leukemia ... A fragile organ The spleen is a fragile and highly vascularized organ
Read More
Blood donation - Useful Information
Useful Information

Blood donation

According to the figures of the Ministry of Health , donations of blood in France amount to 3 million per year, and can save many lives. Who can give? How is the gift? Answers ... Blood is a vital component of the body. And in certain situations, the blood or some of its components, can come to miss cruelly, this is the case for example of road accident victims, burn victims, or people suffering from pathologies, as certain genetic anomalies which affect blood cells, cancers
Read More
Constipation and homeopathy: dietary advice - Useful Information
Useful Information

Constipation and homeopathy: dietary advice

In addition to homeopathy, in case of episodes of repeated constipation, it is advisable to have a diet rich enough in fiber (bread, vegetables, fruits ...) and drink enough water. Be careful not to increase your fiber ration, without bringing enough liquid! It is also recommended to drink water rich in magnesium
Read More