Creatinine: elevated creatinine

With age, it is normal for the kidneys to work less well, with high creatinine in the blood, and a drop in creatinine clearance.

Doctors prescribe a dose of creatinine quite regularly in their patients. Because a malfunction of the kidneys can be very serious consequence. In addition, many drugs impair kidney function, and some drugs can not be given when the kidneys are not functioning properly.

Creatinine in the blood is reported to be too high above 110 micromol / l, or 13 mg / l. It is nevertheless necessary to relativize this result, according to the corpulence of the peson, its age, etc.

The determination of creatinine is therefore a first way to explore the functioning of the kidneys. If the result is high, and especially if the glomerular filtration rate is lowered, the doctor asks for more specific analyzes. In case of kidney damage, the general practitioner will refer you to a kidney specialist: a nephrologist.

The classification of the course and severity of chronic kidney disease is done in different stages. It is the value of glomerular filtration rate (GFR) that counts, and which is expressed in ml / min / 1.73 m 2

The lower this value, the greater the renal problem. Below a GFR of 15, there is end-stage renal failure requiring dialysis.

Here is the classification of the stages of evolution of the renal disease, according to the rate of glomerular filtration, established by the High Authority of Health:

Stadium
DFG (ml / min / 1.73 m 2 )
Definition
1> 90Chronic kidney disease * with normal or increased DFG
2Between 60 and 89Chronic kidney disease * with slightly decreased DFG
3ABetween 45 and 59Moderate chronic renal insufficiency
3BBetween 30 and 44Moderate chronic renal insufficiency
4Between 15 and 29Severe chronic renal insufficiency
5<15Chronic end-stage renal failure

* With markers of renal impairment: albuminuria, hematuria, leucocyturia, or morphological or histological anemias, or markers of tubular dysfunction, persisting for more than 3 months (and at two or three consecutive examinations).

What symptoms can reveal creatinine that increases?

In fact at the beginning ... none! At an early stage of renal failure (and when serum creatinine begins to rise), there are no particular symptoms. The kidneys start to get "tired, " but the body usually has no problem.

At an advanced stage of renal disease, when creatinine rises and glomerular filtration decreases, the patient is tired, suffers from high blood pressure, fluid retention, overweight, heart problems, cognitive disorders, etc.

Prevent kidney failure

It is important to preserve the health of your kidneys, starting by regularly checking their functioning by the creatinine dosage, but also by avoiding exposing the kidneys to certain toxic products: pay special attention to certain drugs, such as anti-inflammatory drugs. Nonsteroidal inflammatory drugs!


Be careful of self-medication and if you have a kidney failure, do not hesitate to tell your doctor if he should prescribe medication. If you have high blood pressure or diabetes, follow your treatment. These ill-treated diseases are at high risk for the health of the kidneys. Finally, remember to drink water regularly.

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