Generic drug from Sectral
Therapeutic class: Cardiology and angiology
active ingredients: Acebutolol
Box of 30
- Prophylaxis of stress angina attacks.
- Treatment of certain rhythm disorders: supraventricular (tachycardias, flutters and atrial fibrillations, junctional tachycardias) or ventricular (ventricular extrasystolies, ventricular tachycardias).
Dosage ACEBUTOLOL ALMUS 400 mg Film-coated tablet Box of 30
the usual daily dose of acebutolol is 400 mg which will be administered either preferably in a single dose each morning, or in two doses, one in the morning and one in the evening (there is a 200 mg dosage form). This dosage may be increased in case of severe arterial hypertension.
- Prophylaxis of effort angina attacks, tachyarrhythmias:
the daily dose may range from 400 to 800 mg (600 mg on average), starting with the lowest dose and adapting, in increments, the clinical dose or the electrocardiogram.
- This medicine MUST NEVER be used in the following cases:
. hypersensitivity to acebutolol,
. asthma and obstructive chronic bronchopneumopathies, in their severe forms,
. heart failure not controlled by treatment,
. cardiogenic shock,
. second and third degree non-paired atrioventricular block,
. Prinzmetal's angina (in pure forms and monotherapy),
. sinus disease (including sinoatrial block),
. bradycardia (<45-50 beats per minute),
. Raynaud's phenomenon and peripheral arterial disorders, in their severe forms,
. untreated pheochromocytoma,
. history of anaphylactic reaction,
. breastfeeding: when treated with acebutolol, breastfeeding is contraindicated, because of a significant passage in the milk,
. combination with floctafenine, sultopride (see interactions),
- Due to the presence of lactose, this drug is contraindicated in case of congenital galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency.
NOT RECOMMENDED :
This drug is generally not recommended when used with amiodarone (see interactions).
Adverse effects Acebutolol Almus
CLINICAL PLAN :
- The most frequently reported:
. cooling of the ends,
. bradycardia, severe if any,
. digestive disorders (gastralgia, nausea, vomiting),
- Much more rarely:
. slowing of atrioventricular conduction or intensification of an existing atrioventricular block,
. heart failure,
. blood pressure drop,
. Raynaud's syndrome,
. worsening of existing intermittent claudication,
. various skin manifestations including psoriasiform eruptions or exacerbation of psoriasis (see precautions for use).
pneumonitis of immunoallergic origin.
AT THE BIOLOGICAL PLAN :
In rare cases, it has been possible to observe the appearance of antinuclear antibodies which only exceptionally accompany clinical manifestations such as lupus syndrome and cede at the end of treatment.